Botulinum toxin, otherwise known as BOTOX, is an FDA approved toxin that enters nerve endings at the injection site and blocks the release of chemicals that cause pain transmission to prevent migraine pain. Botulinum toxin is a preventive treatment used in adults who have 15 or more episodic migraine attacks per month, lasting 4 or more hours per day.
Botox treatments have been proved effective in clinical trials, and are one way to treat chronic migraines.